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Brian Ezekian, MD

House Staff
Start Year: 
Pennsylvania State University (Schreyer Honors College)
Medical School: 
University of Virginia School of Medicine

Clinical and Research Interests

Strategies for desensitization to overcome the HLA barrier to kidney transplantation; antibody-mediated rejection; novel immunosuppressive strategies

What were you looking for in a residency program?

I was looking for a collegial program with a family feel that provided a balanced focus on technical skills, research, and medical education.

What do you like best about living in Durham and the Triangle?

Great people, food, beer, weather, and natural beauty. The Triangle has all the amenities and activities of a large city, but at an affordable price and with a small town vibe.

What do you like to do outside of Duke?

Spending time with my wife and pets, running, hiking, stand-up paddleboarding, cooking

Honors and Awards

  • American Board of Surgery In-Training Examination Award, 2015-2020
  • Apple Seed Resident Teaching Award, 2018-2019
  • Rosenkrantz Award Presentation, 2018
  • American Transplant Congress Young Investigator Award, 2018
  • Alpha Omega Alpha Honor Medical Society Inductee, 2017
  • Federation of Clinical Immunology Societies Travel Grant, 2017


Yoon, J., B. Ezekian, M. Manook, J. Kwun, and S. Knechtle. “alpha-1,3-galactosyltransferase Knockout Porcine Tissue And Organ May Reduce The Risks Of Antibody Mediated Rejection Via Less Rhesus Igm Cross-reactivity.” In American Journal of Transplantation, 19:1057–1057. WILEY, 2019.


Kwun, J., B. Ezekian, P. Schroder, M. Manook, J. Yoon, M. Mulvihill, K. Freischlag, J. Yi, and S. Knechtle. “Costimulation Blockade Modulates Humoral Responses in Highly Sensitized Transplant Recipients.” In American Journal of Transplantation, 19:326–326. WILEY, 2019.


Schroder, P. M., R. Schmitz, Z. Fitch, B. Ezekian, J. Yoon, A. Choi, A. Barbas, et al. “Dual Targeting Desensitization with Carfilzomib Plus Lulizumab Significantly Prolongs Kidney Transplant Survival in Allosensitized Nonhuman Primates.” In American Journal of Transplantation, 19:429–429. WILEY, 2019.


Burghuber, Christopher K., Miriam Manook, Brian Ezekian, Adriana C. Gibby, Frank V. Leopardi, Minqing Song, Jennifer Jenks, et al. “Dual targeting: Combining costimulation blockade and bortezomib to permit kidney transplantation in sensitized recipients.” Am J Transplant 19, no. 3 (March 2019): 724–36.

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Ezekian, Brian, Harold J. Leraas, Brian R. Englum, Brian F. Gilmore, Christopher Reed, Tamara N. Fitzgerald, Henry E. Rice, and Elisabeth T. Tracy. “Outcomes of laparoscopic resection of Meckel's diverticulum are equivalent to open laparotomy.” J Pediatr Surg 54, no. 3 (March 2019): 507–10.

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Freischlag, K., M. Adam, M. Turner, J. Watson, B. Ezekian, P. M. Schroder, C. Mantyh, and J. Migaly. “With widespread adoption of MIS colectomy for colon cancer, does hospital type matter?” Surg Endosc 33, no. 1 (January 2019): 159–68.

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Ezekian, Brian, Michael S. Mulvihill, Paul M. Schroder, Brian F. Gilmore, Harold J. Leraas, Brian C. Gulack, Sarah Jane Commander, et al. “Improved contemporary outcomes of liver transplantation for pediatric hepatoblastoma and hepatocellular carcinoma.” Pediatr Transplant 22, no. 8 (December 2018): e13305.

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Ezekian, Jordan E., Michael S. Mulvihill, Brian Ezekian, Sonya Kirmani, and Kevin Hill. “Refusal of Increased Risk Donor Offers Increases Waitlist Mortality in Pediatric Heart Transplantation.” In Circulation, Vol. 138, 2018.


Freischlag, Kyle, Paul M. Schroder, Brian Ezekian, Morgan L. Cox, Michael S. Mulvihill, Matthew G. Hartwig, and Stuart J. Knechtle. “Improved survival in simultaneous lung-liver recipients and candidates in the modern era of lung allocation.” J Surg Res 231 (November 2018): 395–402.

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Ezekian, Brian, Mohamad A. Adam, Megan C. Turner, Brian F. Gilmore, Kyle Freischlag, Harold J. Leraas, Christopher R. Mantyh, and John Migaly. “Local excision results in comparable survival to radical resection for early-stage rectal carcinoid.” J Surg Res 230 (October 2018): 28–33.

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