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Vascular Surgery Research Laboratory

Photo of Jeffrey Harold Lawson, MD, PhD

Jeffrey Harold Lawson, MD, PhD

Office: 481 Med Sci Res Bldg, Durham, NC 27710
Campus Mail: Box 2622 Med Ctr, Durham, NC 27710
Phone: 919-681-6432

The Vascular Surgery Research Laboratory is directed by Jeffrey Lawson, MD, PhD, and is actively pursuing basic, translational, and clinical research activities related to the fields of blood coagulation, vascular biology, and vascular surgery. The laboratory has become a leader in the field of vascular translational research and has successfully developed a number of molecular, cellular, and tissue engineered technologies through translational animal studies to first-in-man clinical trials.

  • Preclinical and clinical evaluation of human tissue engineered blood vessels
  • Venous remodeling after arterial bypass and vascular access creation
  • Human blood coagulation response to trauma and elective surgery 

Selected Achievements

The laboratory has been involved in the development, preclinical testing, and first-in-man placement of human tissue engineered blood vessels, which has led to publications in Science and Translational Medicine and the Lancet. Members of the lab have published over 100 papers on the topics of blood coagulation, immunology, vascular remodeling, and vascular access.

Advanced Training

We welcome trainees at all levels, including undergraduate, graduate students, medical students, post-doctoral fellows. and surgical trainees.

Contact Us

James Otto, PhD

Jeffrey H. Lawson, MD, PhD

Latest Publications

Gutowski, Piotr, Shawn M. Gage, Malgorzata Guziewicz, Marek Ilzecki, Arkadiusz Kazimierczak, Robert D. Kirkton, Laura E. Niklason, et al. “Arterial reconstruction with human bioengineered acellular blood vessels in patients with peripheral arterial disease.” J Vasc Surg, February 21, 2020.

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Cline, Brendan C., Shawn M. Gage, James Ronald, Waleska M. Pabon-Ramos, Ellen D. Dillavou, Tony P. Smith, Jeffrey H. Lawson, and Charles Y. Kim. “Treatment of Arm Swelling in Hemodialysis Patients with Ipsilateral Arteriovenous Access and Central Vein Stenosis: Conversion to the Hemodialysis Reliable Outflow Graft versus Stent Deployment.” J Vasc Interv Radiol 31, no. 2 (February 2020): 243–50.

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Morrison, Jonathan J., John McMahon, Joseph J. DuBose, Thomas M. Scalea, Jeffrey H. Lawson, and Todd E. Rasmussen. “Clinical implementation of the Humacyte human acellular vessel: Implications for military and civilian trauma care.” J Trauma Acute Care Surg 87, no. 1S Suppl 1 (July 2019): S44–47.

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Kirkton, Robert D., Maribel Santiago-Maysonet, Jeffrey H. Lawson, William E. Tente, Shannon L. M. Dahl, Laura E. Niklason, and Heather L. Prichard. “Bioengineered human acellular vessels recellularize and evolve into living blood vessels after human implantation.” Sci Transl Med 11, no. 485 (March 27, 2019).

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