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Research Laboratories

Our lab focuses on projects that have direct relevance to disorders that are regularly encountered by practicing urologists in the clinic. We are particularly interested in benign urologic disease caused by inflammation in the bladder. We have shown that nod-like receptors (NLRs) and the inflammasomes they form are present in the bladder epithelia where they serve as sensors of sterile damage and...
The Laboratory of Neurourology is headed by Matthew O. Fraser, PhD, and focuses on pelvic visceral function and dysfunction. Dr. Fraser is a classically trained physiologist and a neuroscientist (dual degree PhD). In addition to further elucidating the physiology of pelvic viscera, the laboratory is heavily involved in therapeutic development efforts, including pharmacological, medical devices,...
The Polascik laboratory's research interests focus on translational programs, namely research projects that can have direct consequences on improving patient care and surgical therapy with emphasis on prostate cancer diagnostics, minimally-invasive prostate cancer ablative therapy, observational management of prostate cancer and racial disparities, and kidney cancer.
We are a clinical and translational research team working on cancers of the genitourinary tract. While our group does research pertaining to several different urological cancers, we are particularly interested in bladder and prostate cancer. Our approach to research is highly disease focused, which means that we use a wide variety of research methodologies to investigate a single cancer.