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Bladder Cancer Basic Research

Research Approach

Our laboratory is interested in understanding the immunology of urothelial carcinomas and is examining how these tumors may be manipulating the immune system into a state of paralysis.

Additionally, we are collaborating with Mark Dewhirst, DVM, PhD, and Zeljko Vujaskovic, MD, PhD, to evaluate the role of hyperthermia as a novel therapy that may not only improve the effectiveness of chemotherapy but that may also improve the immune response to urothelial tumors.

Read about our clinical research.

Basic Research Initiatives

In conjunction with Drs. Dewhirst and Vujaskovic, we have developed a novel way of applying hyperthermia to the murine bladder.

Using several murine urothelial tumor models, we intend to use this model to test novel hyperthermia-based treatment regimens.

Future research will evaluate the impact of heat on the immune response to urothelial tumors.

Contact Information

Brant Inman, MD
Associate Professor of Surgery

Duke University Medical Center
467 MSRB-1, Box 2812
Durham NC 27710

Phone: 919-613-6267
E-mail: brant.inman@duke.edu

Research Assistant

  • Wiguins Etienne

Representative Publications

See publications on Pubmed