Howard Levinson, MD

Associate Professor of Surgery
Associate Professor in Dermatology
Assistant Professor in Pathology
Department / Division:
Surgery / Plastic Max & Oral Surgery
DUMC 3181
Durham, NC 27710
Appointment Telephone:
Office Telephone:
  • MD, University of Texas Medical Branch School of Medicine, 1997
  • General Surgery, Brookdale University Hospital and Medical Center (New York), 1997-1998, 1999-2000, 2002-2005
  • Wound Healing (Research), New York University, 1998-1999
  • Wound Healing (Research), Milton S. Hershey Medical Center (Pennsylvania), 2000-2002
  • Plastic and Reconstructive Surgery, Duke University Medical Center, 2005-2008
Clinical Interests:
Breast surgery, including reconstruction, reduction, lifts, augmentation, and gynecomastia; reconstruction, including microsurgery and soft-tissue reconstruction, flaps and grafts; orthopaedic trauma and oncology; skin cancer; extremity reconstruction; complex hernia repair; hand and facial trauma; management of problem scarring and keloids; cosmetic surgery, including facial rejuvenation and fillers; face, forehead, brow, and arm lifts; liposuction; BOTOX; eyelid surgery; abdominoplasty; implants
Research Interests:
Wound Healing
Cell Contractility
Tissue Remodeling
Representative Publications:
  • Bond, JE; Ho, TQ; Selim, MA; Hunter, CL; Bowers, EV; Levinson, H. Temporal spatial expression and function of non-muscle myosin II isoforms IIA and IIB in scar remodeling. Laboratory Investigation. 2011;91:499-508.  Abstract
  • Fearmonti, R; Bond, J; Erdmann, D; Levinson, H. A review of scar scales and scar measuring devices. Eplasty: open access journal of plastic and reconstructive surgery. 2010;10:e43.  Abstract
  • Komatsu, I; Bond, J; Selim, A; Tomasek, JJ; Levin, LS; Levinson, H. Dupuytren's fibroblast contractility by sphingosine-1-phosphate is mediated through non-muscle myosin II. Journal of Hand Surgery (American Volume). 2010;35:1580-1588.  Abstract
  • Yang, J; Erdmann, D; Chang, JC; Komatsu, I; Zhang, Y; Wang, D; Hodavance, MS; Hollenbeck, ST; Levinson, H; Klitzman, B; Levin, LS. A model of sequential heart and composite tissue allotransplant in rats. Plastic and Reconstructive Surgery. 2010;126:80-86.  Abstract
  • Hillyer, S; Vicens, JC; Levinson, H; Bhayani, R; Mesea, L; Chaudhry, R; Fayans, E; Fogler, R. Alveolar soft-part sarcoma of the tongue in a 17-month-old. Ear, Nose and Throat Journal. 2009;88:E4-E9.  Abstract
  • Lee, CC; Golub, R; Singer, AJ; Cantu, R; Levinson, H. Routine versus selective abdominal computed tomography scan in the evaluation of right lower quadrant pain: a randomized controlled trial. Academic Emergency Medicine. 2007;14:117-122.  Abstract
  • Khyrul, WA; LaLonde, DP; Brown, MC; Levinson, H; Turner, CE. The integrin-linked kinase regulates cell morphology and motility in a rho-associated kinase-dependent manner. The Journal of biological chemistry. 2004;279:54131-54139.  Abstract
  • Levinson, H; Moyer, KE; Saggers, GC; Ehrlich, HP. Calmodulin-myosin light chain kinase inhibition changes fibroblast-populated collagen lattice contraction, cell migration, focal adhesion formation, and wound contraction. Wound Repair and Regeneration. 2004;12:505-511.  Abstract
  • Levinson, H; Sil, AK; Conwell, JE; Hopper, JE; Ehrlich, HP. Alpha V integrin prolongs collagenase production through Jun activation binding protein 1. Annals of Plastic Surgery. 2004;53:155-161.  Abstract
  • Levinson, H; Turner, CE; Ehrlich, HP. Integrin-linked kinase: a possible role in scar contracture. Annals of Plastic Surgery. 2004;52:204-211.  Abstract
  • Levinson, H; Hopper, JE; Ehrlich, HP. Overexpression of integrin alphav promotes human osteosarcoma cell populated collagen lattice contraction and cell migration. Journal of Cellular Physiology. 2002;193:219-224.  Abstract
  • Chin, GS; Lee, S; Hsu, M; Liu, W; Kim, WJ; Levinson, H; Longaker, MT. Discoidin domain receptors and their ligand, collagen, are temporally regulated in fetal rat fibroblasts in vitro. Plastic and Reconstructive Surgery. 2001;107:769-776.  Abstract
  • Levinson, H; Peled, Z; Liu, W; Longaker, MT; Allison, GM; Ehrlich, HP. Fetal rat amniotic fluid: transforming growth factor beta and fibroblast collagen lattice contraction. Journal of Surgical Research. 2001;100:205-210.  Abstract
  • Chin, GS; Kim, WJ; Lee, TY; Liu, W; Saadeh, PB; Lee, S; Levinson, H; Gittes, GK; Longaker, MT. Differential expression of receptor tyrosine kinases and Shc in fetal and adult rat fibroblasts: toward defining scarless versus scarring fibroblast phenotypes. Plastic and Reconstructive Surgery. 2000;105:972-979.  Abstract
  • Chin, GS; Liu, W; Steinbrech, D; Hsu, M; Levinson, H; Longaker, MT. Cellular signaling by tyrosine phosphorylation in keloid and normal human dermal fibroblasts. Plastic and Reconstructive Surgery. 2000;106:1532-1540.  Abstract